Carlo Ancelotti's unbeaten team have begun this campaign where they left off last season, when they won the Champions League and LaLiga double.
Real Madrid dropped their first points of the campaign in a 1-1 home draw against Osasuna last Sunday.
Second-placed Barcelona, who sit two points behind Real, will look to put pressure on their arch-rivals.
Villarreal, Real Madrid, Betis and Osasuna share top spot in Spain.
Led by former Manchester City manager Manuel Pellegrini, Copa del Rey champions Betis are flying.
Clement Grenier (left) scores the second goal away at Osasuna.
Us Mallorquinistas will always remember this night. 1,200 fans made the trip to Pamplona and all of them plus us at home suffered all kinds of emotions until Grenier made it 0-2.
Xavi wants to change history against Real Madrid
Real Mallorca fans have a new idol in Kosovan/Albanian 27-year-old striker Vedat Muriqi.
Mallorca in training on Friday.
Monro Bryce's thoughts on RCD Mallorca's next challenge after Wednesday's disaster.
Local authorities will decide whether fans can attend matches and in what numbers.
Emerson played more minutes than any Betis player last season as the Seville side finished sixth in La Liga to qualify for the Europa League.